Have you read Charlie and the Great Glass Elevator? It's the sequel to the original 1964 book Charlie and the Chocolate Factory by Roald Dahl. Pretty far into the book, Charlie and the others fail to get three of Charlie's grandparents out of their bed after returning to Earth. Willy Wonka gives them "Wonka-Vite", a kind of rejuvenation pills, which reduce your age by 20 years per pill. However, they take more than necessary (4 pills instead of 1 or 2), subtracting 80 years, which results in two of them becoming babies.
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